Autoclave, a series of conventions in the Detroit area from 1976 to 1978, was the first con aimed specifically at fanzine fans (as distinguished from the very earliest conventions at which virtually all attendees were involved in fanzines to one extent or another).

It was sponsored by the Metro Detroit SF Society.

Amid the explosion of cons in the 1970s, many fanzine fans tended to be shy and keep to their print-oriented focus. It was felt that a con devoted to their interests might lure some of the hermitlike faneds and fanzine contributors out to meet each other. It was also true that fandom at large was increasingly uninterested in written fanhistory or the arcane minutiae of repro and other details of pubbing one's ish that fanzine fans wanted to talk about at cons.

No one at the time thought of passing the convention around to other groups across the country, which meant that as soon as the Detroit-area fanzine fans who put it on got tired of putting it on, it ceased to be. The rotating fanzine cons Corflu, and then ditto, came along later.

Convention Dates GoHs Chairmen
Autoclave 1 May 28-31, 1976 Gene Wolfe and Donn Brazier Leah Zeldes, Sid Altus, Gary Mattingly
Autoclave II July 22-24, 1977 Donald C Thompson, Don D'Ammassa
Autoclave 3 July 21-23, 1978 Terry Hughes, Derek Carter
Autoclave 4 (cancelled) July 25-27, 1980 Jeanne Gomoll, Dan Steffan Leah Zeldes